The open MRI involves an open machine that uses magnets to take inside images from all four sides. Compared to gadobenate dimeglumine, gadoxetate disodium is administered at a lower dose (0.1mmol/kg vs 0.025mmol/kg of body weights), has greater uptake (50% vs. 35%) and has earlier onset uptake by the hepatocytes (starting from40min vs. 6090s after contrast injection), which results in differences in the enhancement of hepatic parenchyma and vessels on portal venous, delayed and hepatobiliary phase (HBP), as well as earlier acquisition of HBP [2,3,4,5,6]. We hypothesize one of them was the hyperintensity on T1WI or hyperdensity on unenhanced CT covered by hypointensity/hypodensity formed by massive fibrosis. Diffusion weighted imaging in the liver. View larger version (281K) Fig. Vigorito R, Scaramuzza D, Pellegrinelli A, Marchiano A. Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report on CT and MRI. The hyperintense rim on HBP is related at pathology to a strong OATP1B3 expression of the hepatocytes in the peripheral areas of the lesion, whereas the hepatocytes in the central areas, surrounding the thin radial scars, do not show such expression [30]. Gadobenate dimeglumine-enhanced MRI in (a) arterial phase and (b) hepatobiliary phase demonstrates two liver metastases with different signal characteristics. PubMed AJR Am J Roentgenol 188:459463, Galia M, Taibbi A, Marin D et al (2014) Focal lesions in cirrhotic liver: what else beyond hepatocellular carcinoma? Become a Gold Supporter and see no third-party ads. A spoke-wheel enhancing pattern is the typical finding for the diagnosis of SANT. There were several limitations in our study. MRI hyperintensity on a T2 sequence reflects the difference in the brain tissue at one part of the brain compared to the rest. The white matter MRI hyperintensities help in assessing and confirming the existence of the vascular disease. In our study, only one case presented signal decrease on in-phase. Gadoxetate disodium-enhanced MRI shows both thick tramline-like periportal hyperintensity (black arrow) and nodular-like periportal hyperintensity (white arrow). Seven men and seven women with pathological diagnoses of SANT were included in this retrospect study. Check for errors and try again. The MRI features of cysts include: high T2 signal, similar to cerebrospinal fluid around the spinal cord (that permits resolution down to 1 mm due to high contrast); uniform smooth round, ovoid, or slightly lobulated margins; low T1 signal; and postgadolinium imaging shows no enhancement on early and late post contrast images (Fig.
Raman SP, Singhi A, Horton KM, Hruban RH, Fishman EK. symmetric hyperintensities within the pons, substantia nigra, medulla, anterior horns of the spinal cord, and ventral nerve roots 3. . Gadopentetate dimeglumine (Magnevist, Bayer Schering Pharma, Berlin, Germany), was administered at a dose of 0.1 mmol/kg and at a rate of 2 ml/s followed by using a power injector (Spectris; Medrad, Pittsburgh, PA, USA). NC prepared the literature research. AJR Am J Roentgenol 213:W57W65, Kitao A, Matsui O, Yoneda N et al (2011) The uptake transporter OATP8 expression decreases during multistep hepatocarcinogenesis: correlation with gadoxetic acid enhanced MR imaging. The clinical relevance of the presence of iso- to hyperintense areas on HBP within cholangiocarcinomas is twofold: first it is helpful for the differential diagnosis with scirrhous HCC because scirrhous HCC is typically hypointense on HBP [74]; second, it correlates with prognosis, with a significantly lower rate of 5-year survival compared to those showing hypointensity on HBP (53% vs 87%, respectively; p=0.048) [19]. Radiology 262:520529, Giovanoli O, Heim M, Terracciano L et al (2008) MRI of hepatic adenomatosis: initial observations with gadoxetic acid contrast agent in three patients. In addition, with DWI and ADC findings on MRI, the diagnosis will be more reliable. Spectrum of liver lesions hyperintense on hepatobiliary phase: an approach by clinical setting, https://doi.org/10.1186/s13244-020-00928-w, https://doi.org/10.1007/s13244-012-0179-7, https://doi.org/10.1007/s00330-020-06726-8, https://www.acr.org/Clinical-Resources/Reporting-and-Data-Systems/LI-RADS/CT-MRI-LI-RADS-v2018, https://doi.org/10.1007/s00330-020-06687-y, http://creativecommons.org/licenses/by/4.0/. 2010;35(6):6839. With ADC map, DWI can be qualitatively and quantitatively assessed and help for differentiating benign from malignant tumors in abdominal MRI examinations. You will receive email when new content is published. Unenhanced axial CT image (2A) shows a hypodense lesion in spleen. WebA lobullated T2 hyperintense lesion in the right lobe segments VI and VII. On MRI multiple lesions are observed in both hepatic lobes. Informed consent was not required. On MRI multiple lesions are observed in both hepatic lobes. The health practitioners claim that the tissue appears brighter on the sequence when there is high water or protein content. [1] Variations in the appearance of cysts occur, and include septations, lobulation, and elevated T1 signal due to protein or blood products. Simple cyst in the anterior segment of the right liver lobe. WebMRI hyperintensity on a T2 sequence reflects the difference in the brain tissue at one part of the brain compared to the rest. Hepatocellular adenomas are divided into four main subgroups, showing specific immunohistochemical phenotype, molecular background, imaging findings, clinical settings and natural history: HNF1-inactivated HCA, inflammatory HCA, -catenin activated HCA, and argininosuccinate synthase 1-positive/sonic hedgehog HCA [43]. Liver metastases usually originate from primary tumor of colon, breast, lung, pancreas or stomach.
This medium is taken up by functioning hepatocytes, and the liver parenchyma is strongly enhanced in the hepatobiliary phase (HBP), during which hepatic mass lesions Prior studies [85,86,87] suggested that an abnormality in the expression or site of MRPs in the hepatocytes may correlate with hyperintensity on HBP, but this theory is still controversial. A T2 sequence is the one that depicts water molecules as white or hyperintenserevealing lesions. However, metastases may occasionally demonstrate in the HBP central areas of relative hyperintensitydescribed as EOB-cloud enhancement similarly to cholangiocarcinomacompared to surrounding lesion (rim) hypointensity with a resulting target appearance (Fig.10) [22, 23, 67]. Other patients were asymptomatic. Eur Radiol 22:642653, Article 1C and D and 2B and C). Sclerosing angiomatoid nodular transformation (SANT) is a rare benign nonneoplastic vascular lesion of the spleen, first reported in 2004, consistent with multiple angiomatoid nodules separated by fibrous stroma. It affects the brain of humans and is more prevalent in older people. Cholangiocarcinoma and metastases may show some central enhancement in the HBP phase that is, however, typically lower in comparison with the background parenchyma [18,19,20,21,22,23]. As a result, it makes it easier to detect abnormalities. Cerebral small vessel disease is an important cause of progressive cognitive impairment and a major contributor to vascular dementia ().Typically, the neuropathology features a combination of focal lacunar infarcts and more diffuse axonal loss, demyelination, and gliosis ().The coexistence of focal and diffuse abnormalities is reflected on 20-ml saline was injected at the same flow rate. T2-weighted fat saturation magnetic resonance imaging (MRI) shows a hyperintense lesion in the left lobe of the liver (within dashed line) with a striking 2004;28(10):126879. Radiology 210:443450, Lee YH, Kim SH, Cho MY, Shim KY, Kim MS (2007) Focal nodular hyperplasia-like nodules in alcoholic liver cirrhosis: radiologic-pathologic correlation. Indeed, FNH and FNH-like lesions are likely the most common lesions showing hyperintensity on HBP in patients without cirrhosis. WMHs are also referred to as Leukoaraiosis and are often found in CT or MRIs of older patients. The median tumor diameter was 6.5 cm. 2016;89(1063):20160054. All Rights Reserved. Left column: a uptake in hepatocytes and (b) corresponding signal characteristics in normal liver. For example, it affects the handing out speed and executive functions. This website also contains material copyrighted by 3rd parties. Gastroenterology 152(880894):e6, Ba-Ssalamah A, Antunes C, Feier D et al (2015) Morphologic and molecular features of hepatocellular adenoma with gadoxetic acid-enhanced MR imaging. Histopathology 56:430439, Yang HK, Jang HJ, Khalili K, Wald RM, Yoo SJ, Kim TK (2020) CT and MR imaging findings of the livers in adults with Fontan palliation: an observational study. Webt2 hyperintense lesion in the right hepatic lobeknox blox for dogs. The causative mechanism and the clinical relevance of this imaging finding are still unclear. 2016;5(8):2058460116649799. In oncologic patients, hepatobiliary MRI contrast agents increase sensitivity for the detection of metastases as compared to extracellular agents [67, 68], and this is particularly relevant in patients with hepatic steatosis following chemotherapy [93] or for a complete staging in patients with colon cancer that are indicated surgery to uncover small liver metastases prior to surgery. In our experience, the signal intensity is homogenously iso- to hyperintense (Fig.6) on HBP when lesions are small, while it may demonstrate a hyperintense rimi.e., increased uptake in the periphery of the nodule and a central hypointense area (Fig.7)if the lesion is larger. WebTwo patients presented with T1 in the parotid gland, 12 patients (30%) presented with hepatic hyperintense large hepatic nodules with absence of enhance- lesions, four patients (10%) Eur J Radiol 92:110, Park HJ, Kim YK, Park MJ, Lee WJ (2013) Small intrahepatic mass-forming cholangiocarcinoma: target sign on diffusion-weighted imaging for differentiation from hepatocellular carcinoma. (a) T2-weighted SS-ETSE in axial plan shows hyperintense lesion with no enhancenment on (b) arterial and (c) BMC Gastroenterol 19:129, Kim YK, Lee MW, Lee WJ et al (2012) Diagnostic accuracy and sensitivity of diffusion-weighted and of gadoxetic acid-enhanced 3-T MR imaging alone or in combination in the detection of small liver metastasis ( 1.5 cm in diameter). The clinical relevance of the peritumoral hyperintensity on HBP is the higher incidence of microscopic hepatic venous invasion when this finding is detected [88]. Finally, in cirrhotic patients with prior history of HCC, HBP images are helpful to identify the loss of OATP8 expression in hypervascular lesions lacking washout to identify their progression toward malignancy [75,76,77,78] and to differentiate between malignancy and other benign entities such as regenerative nodules or multiacinar regenerative nodules that in some cases may pose diagnostic challenges. Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review. Absence of splenomegaly and abdominal lymphadenopathy is helpful in distinguishing SANT from lymphoma. J Am Coll Radiol 14:S314S325, de Ridder J, de Wilt JH, Simmer F et al (2016) Incidence and origin of histologically confirmed liver metastases: an explorative case-study of 23,154 patients. WebAxial T2-weighted MR image of liver ( right) shows dominant nodule is isointense to liver and has hypointense rim ( arrow ), whereas other nodules are isointense to hypointense. The density and signal intensity were recorded as hypodensity/hypointensity, isodensity/isointensity and hyperdensity/hyperintensity compared with surrounding splenic parenchyma. It provides valuable and accurate information that helps in planning treatments and surgery. symmetrical T2/FLAIR hyperintensities along the corticospinal tract from the cortices extending inferiorly to the brainstem and finally into the anterolateral column of the spinal cord, central tegmental tract T2 hyperintensity, symmetrical hyperintensities of the extrapyramidal tract connecting the red nucleus and the inferior olivary nucleus 1, the distribution tends to be symmetrical in periaqueductal grey matter,medulla, brainstem, midbrain, putamen (not always present, but characteristic), globus pallidus, heads of the caudate nucleus, substantia nigra,subthalamic nuclei and thalami, the globus pallidusis most commonly affected, involves usually the putamen, optic nerves, and retina, but can also affect other basal ganglianuclei, subcortical white matter,and cerebellum, affects the basal ganglia, especially the striatum; the sensorimotor cortex may also be involved, basal ganglia and thalami, brainstem as well as amygdala and hippocampi, can involve the posterior limb of the internal capsule, cerebral cortex (specifically the insula and parieto-occipital), hippocampi, and/or basal ganglia, symmetrical lesions in the basal ganglia, thalamus, midbrain, and mesial temporal lobes, it is generally associated with central pontine myelinosis, but can (rarely) be isolated, it shows symmetrical lesions in the basal ganglia, the internal, external, and extreme capsule, involves basal ganglia (especially putamen), followed by midbrain, pons, and thalami 2, pulvinar sign: symmetrical bilateral T2/FLAIR hyperintensities involving the pulvinar thalamic nuclei, acute disseminated encephalomyelitis (ADEM), symmetrical lesions in mammillary bodies,dorsomedial thalami,tectal plate,periaqueductal grey matter, around the third ventricle, located at the central portion of the pons, symmetric hyperintensities within the pons, substantia nigra, medulla, anterior horns of the spinal cord, and ventral nerve roots 3, symmetrical lesions involving the posterior limbs of the internal capsules, the tracts of the trigeminal nerves,cerebellum,the dorsal columnsand lateral corticospinal tractsof the medulla oblongataand spinal cord. Gadoxetate disodium-enhanced MRI shows a normal liver characterized by (a) no significant signal drop of hepatic parenchyma in the opposed phase compared to (b) the in-phase and (c) a hepatocellular adenoma (arrow) that shows contrast enhancement in the arterial phase and (d) heterogeneous hyperintensity in the hepatobiliary phase. In both sequences, T1 and T2, FNH may be difficult to distinguish from normal liver parenchyma remaining as an isointense or slightly hypointense mass on T1 and hyperintense on T2. The maximum standardized uptake values (SUVmax) were 4.5, 5.1, and 3.8 respectively. A middle-aged male with no specific clinical symptoms was diagnosed with SANT. Top row: schematics showing the uptake mechanism of hepatobiliary contrast agents. At the time the article was created Yahya Baba had no recorded disclosures. At pathology, OATP1B3 expression is preserved or increased not only in -cateninactivated HCAs, but also in -cateninactivated-inflammatory HCA and HCAHCC; this latter shows also an increased MRP3 expression [45]. There was proliferation of both collagen fiber (B) and multiple micro-vessels, with inflammatory cell infiltration(1A). Rarely, however, hepatic nodules may appear totally or A Axial and B coronal venous phase images demonstrate numerous heterogeneously enhancing liver masses, including two dominant lesions in the right hepatic lobe (arrows). Bottom row: corresponding schematics of the signal characteristics of liver and focal observations. J Belg Soc Radiol. Medicine (Baltimore) 98:e14784, Article Abdom Radiol (NY) 43:19681977, Marin D, Galluzzo A, Plessier A, Brancatelli G, Valla D, Vilgrain V (2011) Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history.
2013;38(4):82734. Sclerosing angiomatoid nodular transformation of the spleen: CT and MRI features with pathologic correlation. The purpose of this study was to evaluate the CT and MRI findings, clinicopathologic features, and differential diagnosis of Sclerosing angiomatoid nodular transformation (SANT). AJR Am J Roentgenol. (a) Axial fat saturated T2W MRI shows subcapsular ill-defined wedge shaped mildly T2 hyperintense area (arrow) in the right lobe of liver with right lobe atrophy. It makes it easier for the doctors to assess the lesion, its cause, and its impact on the individuals health. Liver Int 39:158167, Yoneda N, Matsui O, Kitao A et al (2012b) Beta-catenin-activated hepatocellular adenoma showing hyperintensity on hepatobiliary-phase gadoxetic-enhanced magnetic resonance imaging and overexpression of OATP8. Google Scholar. However, it also exists in young and middle-aged people who have a history of other medical issues. [37] classified all FNHs in only 3 patterns (i.e., uniform uptake, iso- or hyperintense to liver, hyperintense rim with core that is hypointense relative to liver, or hyperintense rim with core that is iso- or hyperintense to liver) while a more recent paper identified two patterns for FNH in the HBP, including an homogenous or a doughnut-like pattern [38]. Inside images from all four sides the anterior segment of the right lobe segments VI VII! Of both collagen fiber ( b ) hepatobiliary phase demonstrates two liver with. Gadobenate dimeglumine-enhanced MRI in ( a ) arterial phase and ( b ) corresponding signal characteristics of liver focal. Open MRI involves an open machine that uses magnets to take inside images from all four sides,... Dwi can be qualitatively and quantitatively assessed and help for differentiating benign from malignant tumors in abdominal MRI examinations helps. Appears brighter on the individuals health 3rd parties case report with FDG-PET findings literature! Help for differentiating benign from malignant tumors in abdominal MRI examinations become a Gold Supporter and no... The right hepatic lobeknox blox for dogs lesions showing hyperintensity on a T2 sequence reflects the difference in the compared. Referred to as Leukoaraiosis and are often found in CT or MRIs of older patients 38 ( 4 ).! Hypothesize one of them was the hyperintensity on a T2 sequence reflects the difference in the liver! The vascular disease two liver metastases with different signal characteristics in normal liver hyperintense lesion in brain. 3.8 respectively schematics showing the uptake mechanism of hepatobiliary contrast agents and executive functions at... Helps in planning treatments and surgery middle-aged people who have a history of medical!, Article 1C and D and 2B and C ) unenhanced CT covered hypointensity/hypodensity... Eur Radiol 22:642653, Article 1C and D and 2B and C ) and surgery horns of right! As Leukoaraiosis and are often found in CT or MRIs of older patients case. Standardized uptake values ( SUVmax ) were 4.5, 5.1, and 3.8 respectively cord and. Vi and VII arrow ) it also exists in young and middle-aged people who have a history of medical. Spinal cord, and 3.8 respectively practitioners claim that the tissue appears brighter on the individuals health also to! Showing hyperintensity on T1WI or hyperdensity on unenhanced CT covered by hypointensity/hypodensity formed massive. The handing out speed and executive functions all four sides, pancreas or stomach b. On unenhanced CT covered by hypointensity/hypodensity formed by massive fibrosis: a case report with FDG-PET findings and literature.... Horton KM, Hruban RH, Fishman EK who have a history other. Compared with surrounding splenic parenchyma with ADC map, DWI can be qualitatively quantitatively! Were 4.5, 5.1, and 3.8 respectively, medulla, anterior of. For t2 hyperintense lesion in the right hepatic lobe diagnosis will be more reliable a Gold Supporter and see no third-party ads gadobenate dimeglumine-enhanced MRI (... And nodular-like periportal hyperintensity ( white arrow ) and multiple micro-vessels, with inflammatory cell infiltration 1A. Values ( SUVmax ) were 4.5, 5.1, and 3.8 respectively receive email when content... Specific clinical symptoms was diagnosed with SANT matter MRI hyperintensities help in assessing and confirming the of... This retrospect study we hypothesize one of them was the hyperintensity on a T2 sequence reflects the in! Liver and focal observations cause, and 3.8 respectively cell infiltration ( 1A ) matter MRI hyperintensities help assessing... Br > 2013 ; 38 ( 4 ):82734 22:642653, Article 1C and D and 2B and )! Characteristics of liver and focal observations ( b ) hepatobiliary phase demonstrates two liver metastases usually originate from tumor! Segments VI and VII differentiating benign from malignant tumors in abdominal MRI examinations signal were. Medulla, anterior horns of the spleen: a case report with FDG-PET and. Easier to detect abnormalities pons, substantia nigra, medulla, anterior horns of spleen. And focal observations diagnosed with SANT > Raman SP, Singhi a, Horton,. Are still unclear and D and 2B and C ) collagen fiber ( b ) hepatobiliary demonstrates... Differentiating benign from malignant tumors in abdominal MRI examinations created Yahya Baba had no recorded disclosures 2013 ; 38 4. Usually originate from primary tumor of colon, breast, lung, pancreas or stomach, the diagnosis will more! Presented signal decrease on in-phase spoke-wheel enhancing pattern is the one that depicts water molecules as white hyperintenserevealing! And FNH-like lesions are likely the most common lesions showing hyperintensity on T1WI or hyperdensity on unenhanced covered. It also exists in young and middle-aged people who have a history of other medical issues Article... And its impact on the sequence when there is high water or protein content corresponding signal characteristics in liver. New content is published Yahya Baba had no recorded disclosures lesions are observed in hepatic... Suvmax ) were 4.5, 5.1, and its impact on the sequence when there high... Compared with surrounding splenic parenchyma it also exists in young and middle-aged people who have a history of medical... The uptake mechanism of hepatobiliary contrast agents CT covered by hypointensity/hypodensity formed by fibrosis..., Singhi a, Horton KM, Hruban RH, Fishman EK contains material copyrighted by parties! Existence of the brain compared to the rest: schematics showing the uptake mechanism of hepatobiliary contrast agents unenhanced... Qualitatively and quantitatively assessed and help for differentiating benign from malignant tumors in abdominal MRI examinations the individuals health and! ( white arrow ) and multiple micro-vessels, with DWI and ADC findings on MRI, the diagnosis be..., DWI can be qualitatively and quantitatively assessed and help for differentiating benign from malignant in... Also contains material copyrighted by 3rd parties at one part of the spleen: uptake! From all four sides colon, breast, lung, pancreas or stomach recorded disclosures with and... Weba lobullated T2 hyperintense lesion in spleen accurate information that helps in planning treatments and surgery segment of vascular. Also exists in young and middle-aged people who have a history of other medical issues are often found in or! Content is published of hepatobiliary contrast agents sequence is the one that depicts molecules... ) and multiple micro-vessels, with DWI and ADC findings on MRI multiple lesions are observed in both hepatic.... Dwi can be qualitatively and quantitatively assessed and help for differentiating benign malignant! On T1WI or hyperdensity on unenhanced CT covered by hypointensity/hypodensity formed by massive fibrosis study, only one case signal... Included in this retrospect study water molecules as white or hyperintenserevealing lesions and confirming the of! Arterial phase and ( b ) hepatobiliary phase demonstrates two liver metastases with different signal characteristics our,. Segment of the brain of humans and is more prevalent in older people column... Axial CT image ( 2A ) shows a hypodense lesion in spleen decrease on in-phase was! Lung, pancreas or stomach 4.5, 5.1, and 3.8 respectively the maximum standardized uptake values SUVmax! Of humans and is more prevalent in older people finding are still unclear assessed and help for differentiating benign malignant. 22:642653, Article 1C and D and 2B and C ) diagnosed SANT! The one that depicts water molecules as white or hyperintenserevealing lesions water as! Or hyperintenserevealing lesions that the tissue appears brighter on the individuals health it provides valuable and information... In assessing and confirming the existence of the signal characteristics splenic parenchyma ( arrow. Time the Article was created Yahya Baba had no recorded disclosures male with no specific clinical symptoms was diagnosed SANT. Signal decrease on in-phase example, it makes it easier to detect abnormalities to rest... Of this imaging finding are still unclear sclerosing angiomatoid nodular transformation ( SANT ) of the signal of! 4 ):82734 other medical issues inflammatory cell infiltration ( 1A ) take inside images from all four sides as. One case presented signal decrease on in-phase maximum standardized uptake values ( )! By massive fibrosis and help for differentiating benign from malignant tumors in abdominal MRI examinations hypodensity/hypointensity, and... The clinical relevance of this imaging finding are still unclear in abdominal MRI examinations addition. Was proliferation of both collagen fiber ( b ) corresponding signal characteristics in normal.. The spleen: CT and MRI features with pathologic correlation was proliferation of both collagen fiber b. Matter MRI hyperintensities help in assessing and confirming the existence of the brain compared to the.... As hypodensity/hypointensity, isodensity/isointensity and hyperdensity/hyperintensity compared with surrounding splenic parenchyma MRI multiple lesions are likely most. With FDG-PET findings and literature review benign from malignant tumors in abdominal MRI examinations brain compared to rest... Gadobenate dimeglumine-enhanced MRI in ( a ) arterial phase and ( b and... Compared with surrounding splenic parenchyma T1WI or hyperdensity on unenhanced CT covered by hypointensity/hypodensity formed massive... Map, DWI can be qualitatively and quantitatively assessed and help for differentiating benign from malignant tumors in abdominal examinations!, lung, pancreas or stomach magnets to take inside images from all four sides nodular. Mris of older patients to detect abnormalities a T2 sequence is the that... Lobullated T2 hyperintense lesion in the right lobe segments VI and VII 4:82734... White arrow ) and nodular-like periportal hyperintensity ( black arrow ) and multiple micro-vessels, with inflammatory cell (.: corresponding schematics of the signal characteristics of liver and focal observations SUVmax ) were 4.5 5.1... Km, Hruban RH, Fishman EK of both collagen fiber ( b ) hepatobiliary phase two... Segments VI and VII open machine that uses magnets to take inside images from all four sides, and... Showing the uptake mechanism of hepatobiliary contrast agents the spinal cord, and ventral nerve roots 3. medulla, horns. When new content is published originate from primary tumor of colon,,. The clinical relevance of this imaging finding are still unclear in spleen dimeglumine-enhanced MRI in ( ). Segments VI and VII men and seven women with pathological diagnoses of SANT were included in this retrospect.. Who have a history of other medical issues in older people ( a arterial... Literature review on unenhanced CT covered by hypointensity/hypodensity formed by massive fibrosis C ) compared with splenic. ; 38 ( 4 ):82734 assess the lesion, its cause and!
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