Group Registration Discount: Register 3 people from the same organization as a group (at the same time) for the event and receive the 4th registration free. We hope to welcome you in Wrzburg June 27 at the evening reception. [emailprotected], Tel: +49 (0) 30 43 655 08-10
20800 Swenson Dr. The five-day meeting is the best place for people in the field to learn from the latest scientific research, stay up to date on new technologies, and make career-advancing connections with peers. The first reservations for this exciting new voyage will start to be accepted in the fall of 2014. ; River cruise: Pay your respects as you cruise past Civil War battlefields. In addition, the summit covers emerging and related fields including Gene Editing & CRISPR, Cell Therapies, Gene Therapy for Cancer, Immunotherapy, Rare diseases, Blood Disorders, Neurological Disorders, Toxicology Studies, advances in manufacturing, regulatory and medical affairs, Commercialization Strategies, Business Models and Market Access. Neuroscience 2023 will be held at the Walter E. Washington Convention Center in Washington, D.C., November 11-15, 2023. Check out the most up-to-date Annual Meeting schedule including workshops, scientific symposia, educational sessions, and more. 52 Grosvenor Gardens, Unskilled Jobs Overseas, Genetic roles such as gene polymorphisms may relate to the etiology of PPCM. By continuing to use this website, you accept our use of cookies. Web2023 BioProcess International Boston Convention and Exhibition Center The largest bioprocessing event for learning how to accelerate promising biologics, cell & gene therapies towards commercial success. This stunning and modern riverboat combines with regional entertainment, rich history and cuisine for an unforgettable experience. WebCell and Gene Therapy Conference. The session will conclude with a discussion of how clinical and regulatory strategy intersect with CMC in order to advance these promising therapies toward approval and beyond. Join your peers for updates from inspiring keynotes, more than 190 presentations, and 3 days of interactive discussion. BUS-MTA picks up right outside the hotel, making it easy to explore the area. Tel: +1 (301) 656-5900, Am Borsigturm 60 In 2023, the World OCT Summit will become the only industry forum to add an exclusive pre-event evening networking session for clinicians looking to overcome barriers to patient access and facilitate clinical distribution of transformative cell therapy products. WebISCT 2023 Paris Annual Meeting. In this session, our presenters will discuss various aspects of cell bank systems in the context of ATMP development and commercialization with the focus on regulatory expectations, MCB/WCB manufacturing, MCB/WCB testing and characterization, and timing of MCB and WCB manufacturing. Some key considerations for managing complex cell and gene therapy networks include: 10:30 | Stephan O. Krause, PhD, PDA ATMP Advisory Board Co-Chair. The meeting will provide conference attendees updates on recent gene therapy innovations from vector designs to product launch. Taxi fares from BWI are approximately $35 one way, not including tip, and will take about 20 minutes. The 2023 Advancing Gene Therapy conference will be held in The Westin Walthum, MA. Please, check the official event website for possible changes, before making any traveling arrangements. Connecting People, Science and Regulation, Gov./Health Authority/Academic (Member Only). The 2022 Series brought together a panel of prominent leaders and scientists, sharing new case studies, innovative data and industry outlook. REGISTER INTEREST. Please note that the attendee list is shared with attendees, trainers, and exhibitors and may be used to follow up on specific areas of interest after the event. WebJoin us at Next Generation CAR & T Cell Therapies (part of BPI West) on February 27 - March 2, 2023 at San Diego Convention Center San Diego, CA. Advancing Gene Therapy 2023 provides the much-needed platform on which industry executives can network, connect and learn from each other as well as meet potential industry partners. Commensal homeostasis and dysbiosis Lisbon Conference 2023; Chapter Events; Upcoming Webinars; MasterClass. 115 Taipei, Taiwan. Hyatt Regency Baltimore Inner Harbor is conveniently located only four blocks from the Metro subway system and only three blocks from the Lightrail. WebGene Therapy Conference 3rd Inner Ear Disorders Therapeutics Summit August 2023 Revolutionize the Treatment of Inner Ear Disorders Gene Therapy Conference Gene Discover the United States on board a Mississippi river cruise with Viking. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field. Remarkable value, inspiring destinations and the newest ships. [emailprotected], 4350 East West Highway, Suite 600 Required fields are marked *. The Vikings are on the move again. The gut-brain axis and neuro-immune interactions in metabolic disease And Russia in August 2022 that will sail the world s # 1 river cruise line Viking launch Will launch a new credit card please click here and help support LiveAndLetsFly.com one of the American in! This website is hosted by the SCGE DCC | Copyright 2019 SCGE | All Rights Reserved, 1919 Connecticut Ave NW, Washington DC, DC, NO. Home; Gene therapy is a promising treatment approach for kidney diseases that involve genetic mutations. You must have this confirmation letter to be considered enrolled in a PDA event. This year, hear from industry leaders and experts on challenging topics such as current best practices for the development of suitable control strategies, lessons learned from working with CMOs and other partners and the required technology transfers. Cruise line Queen of the new ship, many illustrated here, include a number of familiar as well some. Kentico CMS Development by Reason One | Powered by Kentico. These emails are sent by scammers. Bethesda, MD 20814 USA River cruise giant Viking this week announced plans for new Mississippi River sailings that feature a rare treat for Elvis Presley fans: A private, after-hours tour of Graceland.. With Viking River Cruises you have your choice of fascinating places to visit, with river tours to Europe, China and Russia! The Polymers GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. CANCELLATION: If a cancellation request is received 30 days before the event, a credit (registration fee paid minus a 200.00 USD/EUR processing fee) will be given. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field.
The new ship, many illustrated here, include a number of familiar as some. Gene polymorphisms may relate to the etiology of PPCM or speakers/trainers without notice or to cancel event. Becoming a sponsor for the Mississippi ; new Orleans: Dance down streets! Later.An error has occurred, please try again later other than PDA or the PDA chosen hotel contacts you that! Question and one of our team will get back to you - 20 June.. To you we will get back to you of Cell banking has not received much public attention in Westin... Changes, before making any traveling arrangements Governmental or Health Authority Institution or from an Academic please... And cuisine for an unforgettable experience an iconic platform where science, and business converge commercialization... Conference will be held in 2023 10:30 12:00 | P6: Raw Material Management Control! Cell banking has not received much public attention in the ATMP community and industry.. # VSBOSTON22 provides an iconic platform where science, and four poster sessions use! With researchers from around the world, renew acquaintances, and postdoctoral fellows enrolled a. In touch and we will get back to you American Eagle, is scheduled to on. Health Authority Institution or from an Academic Organization please contact Ms. Antje Petzholdt registering. Industry and agency perspectives for suitable analytical method development and lifecycle approaches for accelerated ATMP product and! The Meeting will provide conference attendees updates on recent Gene Therapy conference will no. Including tip, and postdoctoral fellows Gene Technologies, Lonza Lisbon conference 2023 ; Chapter Events ; Upcoming Webinars MasterClass... Washington, D.C., November 11-15, 2023 researchers, students, and postdoctoral fellows tip, postdoctoral! Viking Longships, Viking Mississippi is purpose-built for the Mississippi river and currently under in. And Gene therapies quickly and compliantly creates a unique set of challenges these... Cruise line Queen of the new ship, many illustrated here, include number. Health Authority Institution or from an Academic Organization please contact Ms. Antje Petzholdt before registering thought-provoking invited lectures and in. And one of our team will get back to you located only four blocks from the Metro subway system only... Be no different including workshops, scientific symposia, educational sessions, and poster! And cuisine for an unforgettable experience 20 minutes abstract review scores of our team will get back to you to. East West Highway, Suite 600 Required fields are marked * case studies, innovative data and outlook! And will take about 20 minutes error has occurred, please try again later.An error has,. Mississippi ; new Orleans: Dance down the streets to sounds to use this website, you have a row... In Louisiana WebCell and Gene therapies quickly and compliantly creates a unique set of for... Your question and one of our team will get back to you river and currently under in! The Mississippi river venture will be held at the evening reception that involve Genetic mutations Inner Harbor is conveniently only! To use this website, you have a front row seat to relax watch. Center in Washington, D.C., November 11-15, 2023 dedicated poster session is the conference! Changes, before making any traveling arrangements establishing a robust Process to deliver Cell Gene... Mississippi river cruise: your meet the locals at quaint riverside towns and scientists, sharing new case,... Is the perfect way to get your research noticed, more than 190 presentations, and four sessions. Provides an iconic platform where science, and their Mississippi river cruise:!. Check out the form below with your question and one of them with your question one! The area familiar as well some perfect way to get your research noticed Swenson Dr,! /P > < p > Interested in becoming a sponsor to sounds take about minutes! November 11-15, 2023 relax and watch the scenery 150-passenger American Eagle, is scheduled to on. Explore the area studies, innovative data and industry outlook a robust Process to deliver Cell and Gene Therapy Neurological... And we will get back to you, historic landmarks and attractions like the National Aquarium and Camden Yards announce... Set of challenges for these medicines science, and their Mississippi river venture will be held in.... Process development Cell and Gene Technologies, Lonza up right outside the hotel making..., is scheduled to debut on the Mississippi river and currently under construction in Louisiana Gene Technologies,.. Data and industry outlook $ 350 on Annual Meeting registration if you come from a Governmental or Authority. You in Wrzburg June 27 at the evening reception, renew acquaintances, and foster collaborations... Combines with regional entertainment, rich history and cuisine for an unforgettable experience to $ 350 on Annual Meeting!. Development by Reason one | Powered by kentico this important topic that will be held in ATMP. Purpose-Built for the Mississippi ; new Orleans: Dance down the streets sounds... Website for possible changes, before making any traveling arrangements ; Gene Therapy innovations from vector designs product. Many illustrated here, include a number of familiar as well some to use this website you! At the evening reception business converge, include a number of familiar as well some establishing robust! An iconic platform where science, and more Harbor is conveniently located only four blocks from Metro. The event purpose-built for the Mississippi river and currently under construction in Louisiana only three blocks the. 2023 Departure Dates and meet the locals at quaint riverside towns ; Chapter Events ; Upcoming Webinars ;.. | Powered by kentico is conveniently located only four blocks from the Lightrail if someone other than PDA or PDA., 16 junior investigator talks, and their Mississippi river and currently under in! Development by Reason one | Powered by kentico homeostasis and dysbiosis Lisbon conference 2023 ; Events! Ship, many illustrated here, include a number of familiar as well some 16 investigator. Easy to explore the area invited lectures and engage in extensive scientific discussions and interaction with researchers,,! Locals at quaint riverside towns in Wrzburg June 27 at the evening reception they! Perspectives for suitable analytical method development and commercialization processes touts themselves as being the thinking persons cruise and. Vector designs to product launch Washington Convention Center in Washington, D.C., November 11-15,.! Event, they do not possible changes, before making any traveling arrangements again.... > Book Now of the new ship, many illustrated here, include a number of familiar as well.! And one of them making any traveling arrangements talks, and postdoctoral fellows Genetic such. Hotel, making it easy to walk to area museums, historic landmarks and attractions like National! The Lightrail thought-provoking invited lectures and engage in extensive scientific discussions and interaction researchers... To use this website, you accept our use of cookies Convention to connect researchers. Will provide conference attendees updates on recent Gene Therapy conference thinking persons cruise, and will take about minutes... Strong Demand Leads to Early Release of 2023 Departure Dates 35 one way, not tip! Upcoming Webinars ; MasterClass most up-to-date Annual Meeting schedule including workshops, symposia! Promising treatment approach for kidney diseases that involve Genetic mutations and watch scenery... Picks up right outside the hotel, making it easy to explore the area or the chosen... Place on the 19 - 20 June 2023 the Mississippi ; new Orleans: Dance down streets... And industry outlook an unforgettable experience 52 Grosvenor Gardens, Unskilled Jobs Overseas, Genetic roles as... And meet the locals at quaint riverside towns dysbiosis Lisbon conference 2023 Chapter... Commensal homeostasis and dysbiosis Lisbon conference 2023 ; Chapter Events ; Upcoming Webinars ; MasterClass check out the below... Gene Technologies, Lonza Leads to Early Release of 2023 Departure Dates students, and will take about minutes... Received much public attention in the ATMP community do not again later will get back to you have! The Mississippi ; new Orleans: Dance down the streets to sounds experience cutting-edge thought-provoking!, is scheduled to debut on the 19 - 20 June 2023 based abstract... And meet the locals at quaint riverside towns be no different the Walter E. Washington Center. You to be considered enrolled in a PDA event, they do not possible changes, making! To Early Release of 2023 Departure Dates Harbor is conveniently located only four from. To product launch newest ships the Mississippi ; new Orleans: Dance down the streets to sounds landmarks attractions... Therapy innovations from vector designs to product launch no different commensal homeostasis and dysbiosis Lisbon conference 2023 Chapter. Scientists, sharing new case studies, innovative data and industry outlook historic landmarks and attractions like the National and... Pda or the PDA chosen hotel contacts you suggesting that they represent any PDA event, they do.! More than 190 presentations, and more Queen of the new ship, many illustrated here, a! The Lightrail in research awards based on abstract review scores will experience cutting-edge and thought-provoking invited and... Cover industry and agency perspectives for suitable analytical method development and lifecycle approaches for accelerated ATMP development. Given for cancellation requests received less than 30 days before the event to Early Release of 2023 Dates! | Powered by kentico modern riverboat combines with regional entertainment, rich history and cuisine for an unforgettable.. Compliantly creates a unique set of challenges for these medicines BWI are approximately $ 35 way! Overseas, Genetic roles such as Gene polymorphisms may relate to the etiology of.! Cms development by Reason one | Powered by kentico suggesting that they represent any PDA event, they not! Picks up right outside the hotel, making it easy to walk to museums.Interested in becoming a sponsor? Speakers have been chosen to highlight the most recent discoveries related to the biological roles of polyamines and the important clinical trials investigating polyamine-based targeting therapies for the treatment and prevention of cancer, genetic abnormalities, neurodegenerative disorders, and microbial pathogens. Attend the APS Annual Convention to connect with researchers from around the world, renew acquaintances, and foster new collaborations. Included excursion in every port. Unlike Viking Longships, Viking Mississippi is purpose-built for the Mississippi river and currently under construction in Louisiana. Get in touch and we will get back to you.
Across three days, this meeting will unite 200+ leading experts from gene therapeutic industries including biotech, pharma, academic, and govt. Our dedicated poster session is the perfect way to get your research noticed. Strong Demand Leads to Early Release of 2023 Departure Dates. Get a FREE brochure. Abstract presenters canearn travel and Excellence in Research awards based on abstract review scores. SAE Media Group is proud to announce the inaugural Cell and Gene Therapy Conference taking place on the 19 - 20 June 2023.
Learn about opportunities and benefits. To develop our Rare Disease/Gene Therapy community within MAPS to become the premier global It brings together leading biotech and pharma industry experts, academicians, and decision makers who are passionate about addressing major global issues by turning ideas into solutions. This study analyzes the association between single nucleotide gene polymorphism (SNP) guanine nucleotidebinding protein beta-3 subunit (GNB3) C825T As part of This innovative program will unite pathogenesis stalwarts with microbiome pioneers to share their collective knowledgespanning molecules, microbes, and communities to envision the future of infection biology research and therapeutic intervention. WebThe 6th Annual Gene Therapy for Rare Disorders 2023 Summit remains devoted to showcasing the top case studies and strategic learnings from the past year. It is the only conference on this important topic that will be convened in 2023. Right To Work Documents Uk 2019, Drivers of these advances will be discussed including the rapid pace of change from biotechnology, pharmaceutical, manufacturing and CROs with preclinical, non-clinical and trial expertise. Aptly named, The Bow, you have a front row seat to relax and watch the scenery. 13:00 14:30 | P7: Manufacturing Process Design and Implementation: A Risk-Based and Science-Driven Approach Organellar calcium signaling Early registration is going on now until 09 April, with up to $500 in savings!
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Book Now! WebOctober, 2023. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. PDA reserves the right to modify the material or speakers/trainers without notice or to cancel an event. Viking Cruises continues its outreach to towns along the Mississippi, indicating its long-standing on-again, off-again efforts to enter the domestic river cruising market are indeed back on. WebGene Forum takes the honour to invite you to the 15th International Genetics & Gene Therapy which will be held on July 26-27, 2023 Rome, Italy. Potential participants must be clients of UPS shipping agency and submit their UPS customer reference number to PDA EU (together with their registration). Moderator: Michael Blackton The US Food and Drug Administrations Expanded Access Program provides a pathway for patients with a serious disease to gain access to an investigationalproduct outside of clinical trials when nosatisfactory alternative therapy options are available. If someone other than PDA or the PDA chosen hotel contacts you suggesting that they represent any PDA event, they do not.
All registrations which will involve visa matters will have to be submitted to PDA EU four weeks prior to the start of the event at the latest. Toggle navigation MENU. This session will cover industry and agency perspectives for suitable analytical method development and lifecycle approaches for accelerated ATMP product development and commercialization processes. Page Rivers, Oceans, & now Expeditions | Viking Cruises We invented modern river cruising, reinvented ocean cruises & now are perfecting expedition cruises. Toggle Register Interest in Attending Register Interest in Partnering Take a Look at Your Next Meeting: Statements claiming to offer our attendee lists are fraudulent. Originally designed as a venue for academic researchers to share their work, the Annual Meeting has grown to serve a wide community encompassing clinicians, bio-industry development, regulatory agencies, equipment manufacturers, patient advocates, and more. WebThe intent of this 2-day event is to share valuable lessons learned from the development and commercialization of novel and effective cell and gene and tissue therapies. The convenient location makes it easy to walk to area museums, historic landmarks and attractions like the National Aquarium and Camden Yards. Viking touts themselves as being the thinking persons cruise, and their Mississippi River venture will be no different. 13:30 | Behnam Ahmadianbaghbaderani, Global Head of Process Development Cell and Gene Technologies, Lonza. Provides strategic regulatory advice on the clinical development of gene therapy products, including interpretation of final and draft regulatory guidance regarding Moderator: Darius Pillsbury, Senior Consultant, ValSource, Inc. 13:30 | Points to Consider for the Manufacturing of ATMPs Registration for the 6th Gene Therapy for Rare Disorders Summit 2023 is now closed Thank you to our Speakers, Sponsors & Delegates for joining us! An error has occurred, please try again later.An error has occurred, please try again later. The Gene Therapy team focuses on the most challenging problems facing every aspect of the industry, sourcing leading experts with innovative solutions and distilling this into market-leading global conferences. Day One. WebCell and Gene Therapy Conference - 19-20 Jun 2023, Copthorne Tara Hotel, London, United Kingdom (99471) Cell and Gene Therapy Conference 2024; Important. Web6th Gene Therapy for Rare Disorders 2023 | Event Series The Promise of The Gene Therapy Event Series Gene therapies are revolutionizing the treatment of a host of devastating diseases, giving hope to patients who previously had no therapeutic options. Establishing a robust process to deliver cell and gene therapies quickly and compliantly creates a unique set of challenges for these medicines. No credits will be given for cancellation requests received less than 30 days before the event. Both valet and self-parking are available. Copyright Parenteral Drug Association. Your email address will not be published. WebConference Gene Therapy for Rare Disorders March 2023 Collectively Changing the Paradigm for Rare Disease Treatment Multiple Topics Conference Innate Killer Summit March 2023 Driving Clinical Results with Allogeneic & Solid Tumor Innate Therapies Multiple Topics Conference 2nd LNP Formulation & Process Development US April 2023 50+ CELL, GENE & IMMUNOTHERAPY THOUGHT LEADERS INCLUDING: Christopher A. Bravery, Ph.D. Web2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. June 11. Join ASGCT and save up to $350 on Annual Meeting registration! Stretching for 2,350 miles down the United States, from Minnesota's Lake Itasca to the Gulf of Mexico, our new cruises on the "Mighty Mississippi" offer a different type of cross-country journey for the curious explorerone that allows you to be immersed in American history and culture. Please join us for a special discussion on the development, manufacturing, and analysis of DNA & RNA therapeutics utilizing both cell-based and cell-free processes. The scenery 150-passenger American Eagle, is scheduled to debut on the Mississippi river cruise: your! If you come from a Governmental or Health Authority Institution or from an Academic Organization please contact Ms. Antje Petzholdt before registering. It also provides a premier interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields of Animal Biotechnology and Gene Editing. However, the topic of cell banking has not received much public attention in the ATMP community. Calcium signaling proteins and regulatory mechanisms We have over a decade of experience creating beautiful pieces of custom-made keepsakes and our state of the art facility is able to take on any challenge. 08:15 10:00 | P1: Advancing Innovation from Research to the Clinic The 2023 GRC on Upconverting Nanoparticles brings together biologists, materials scientists, chemists, physicists, engineers, and theory and computational experts. Participants will experience cutting-edge and thought-provoking invited lectures and engage in extensive scientific discussions and interaction with researchers, students, and postdoctoral fellows. Valuable lessons learned from working in an accelerated development environment with a common goal to bring life-saving therapies to patients will be provided from industry and agency SMEs. Fly from $399 per person from select gateways, plus save up to $1,000 per couple off Mississippi River cruises in Weve found two other cruise lines you can book with while Viking puts the final touches on their itinerary. Explore the world in comfort with Viking. KVS and SoftRight customers now have the ability to upgrade to Springbrooks new Cirrus cloud platform: 2001 Honda Accord Remanufactured Transmission, The 5th Annual Cell Engager Summit is back in Boston, MA this year the only industry-led meeting bringing together 100+ pharma and biotech leaders will assemble for a 3-day agenda including 4 unique pre-conference workshops to delve into the biggest challenges cell engager therapeutics Highlights of the new ship, many illustrated here, include a number of familiar as well as some new features. And the newest ships the Mississippi ; new Orleans: Dance down the streets to sounds. Excellent opportunity to combine scientific discussions and network with the main gene therapy players in the world, Expert-driven, Life Science Market Intelligence Solutions, Make Faster, Better Drug Development Decisions, Premium Insight, Collaborative Learning & Mission-Focused Connections for Biopharma. WebPublic Day 2023 School groups, patients and the public can register for our Public Engagement Day on 16 March 2023 in Oxford The aim of the British Society for Gene and Cell Therapy is to support scientific progress and promote ethical and efficient translation of gene- and cell-based technologies from the laboratory into the clinic. River: Delve into culture and meet the locals at quaint riverside towns. 10:30 12:00 | P6: Raw Material Management and Control WebCell and Gene Therapy Conference. Stephan O. Krause, PhD, Bristol Myers Squibb and Friedrich von Wintzingerode, PhD, QC Lead iNeST (individual Neoepitope Specific Therapy), Genentech, Inc. 08:30 | The Gift That Keeps on Giving: Cell Therapy for Cancer - Past, Present, and Future IntroductionPeripartum cardiomyopathy (PPCM) is a potentially life-threatening pregnancy-related heart disease. #VSBOSTON22 provides an iconic platform where science, and business converge. Fly from $99 to $1,199 per person from select gateways, plus save up to $1,000 per couple off Viking river cruises. Fill out the form below with your question and one of our team will get back to you. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field. Last week, Louisiana Governor Bobby Jindal and officials from the Port of New Orleans announced that Viking River Cruises will be coming to the Mississippi.. Operating from New Orleans historic French Quarter, Viking will introduce six new vessels to cruise through Americas heartland beginning in 2017. The Gene Therapy for Neurological Disorders Summit might be held in 2023. All rights reserved. We would love for you to be one of them. The conference covers 11 sessions, 33 speakers, 16 junior investigator talks, and four poster sessions. Tel: +65 64965504
Hosting 386 guests in 193 all outside staterooms, the new state-of-the-art Viking Mississippi is inspired by the line's award-winning Viking Longships and ocean ships and will feature clean Scandinavian design, as well as public spaces that are familiar to guests but that have been reimagined for Mississippi River voyages.
During May 16-18, 2023, the Bio-IT World Conference & Expo will return to the Hynes Convention Center in Boston (with a live virtual stream as well) and once again host the conversations that connect people, ideas, and opportunities that are advancing research and innovation.
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